Combinatorial Ion Sensors
Abstract
The objective is to develop a massively parallel combinatorial method for preparing and screening ionophores which selectively bind group IIB and divalent transition metals. The accomplishments were: During the past year, we have prepared for and begun preparation of an encoded combinatorial library of cyclen-based receptors and also validated a color-based assay for detecting certain metal-binding ligands. The latter study was designed as a positive control to show that good metal-binding polymer-supported ligands could be detected visually from a library of relatively poor ionophoric ligands.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 14, 1994
- Accession Number
- ADA276567
Entities
People
- W. C. Still
Organizations
- Columbia University