Sensible Heat Loss After Systemic Anticholinergic Treatment
Abstract
Systemic atropine administration decreases eccrine sweat gland release via competitive inhibition at cholinergic receptors and augments skin blood flow by a yet unknown mechanism. Increased skin blood flow promotes auxiliary radiative and convective heat flux by 20-100% in both warm and cold environments. These studies showed that the systemic dose of atropine (2 mg, im) was sufficient to block cholinergic sweat gland activity and core and skin temperatures were higher after atropine compared to control experiments. There was an enhanced skin blood flow thermosensitivity to esophageal temperature drive following atropine administration.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1994
- Accession Number
- ADA277594
Entities
People
- L. A. Stephenson
- M. A. Kolka
- R. R. Gonzalez
Organizations
- United States Army Research Institute of Environmental Medicine