Production of Anti-Ferret IgA Antibodies; and production of monoclonal antibodies

Abstract

A Production of anti-ferret IgA antibodies. Status: Rabbit immunization completed. Immune serum collected. Currently cross-adsorbing serum with ferret IgG. Purification of lipopolysaccharide from Shigella and Campylobacter species. Status: Preparation of Shigella LPS completed. Material delivered to Navy. Production of Campylobacter LPS on hold. Development of an enzyme immunoassay for the detection of enteroaggregative Escherichia coli heat- stable toxin. Status: This portion of the project has been suspended. Production of monoclonal antibodies against strain-specific antigenic epitopes on amplylobacter coli flagella. Status: have completed screening hybridomas from two fusions. Flagellin reactive MAbs produced; no strain-specific MAbs identified. Preparing for third fusion.

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Document Details

Document Type
Technical Report
Publication Date
Apr 26, 1994
Accession Number
ADA279534

Entities

People

  • John M. Ivy

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Antibodies
  • Bacterial Proteins
  • Biomedical Research
  • Biotechnology
  • Cells
  • Cellular Structures
  • Contracts
  • Electron Microscopy
  • Escherichia
  • Escherichia Coli
  • Guillain-Barre Syndrome
  • Immune Serums
  • Lipopolysaccharides
  • Materials
  • Molecular Genetics
  • Production
  • Reactivities

Fields of Study

  • Biology

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