Molecular Recognition as Shown by the Solvent Extraction of (R)- and (S) -Alpha-(1-Naphthyl)Ethyl Ammonium Picrate or Orange 2 by Chiral Pyridino-Crown Ethers

Abstract

A solvent extraction technique was used to determine equilibrium constants for the reaction of ALPHA-(L -NAPHTHYL)ETHYLammonium ions (R)- and (S) -isomers with chiral substituted pyridino- 18-crown-6 ligands in a water- chloroform system. Selectivity coefficients and stability constants for the interaction in chloroform solutions were calculated. The selectivity patterns are similar to those found by the 1H NMR technique. Thus, this method may be a simple and rapid way to determine enantiomeric recognition.

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Document Details

Document Type
Technical Report
Publication Date
May 12, 1994
Accession Number
ADA280157

Entities

People

  • Alexander Y. Nazaraenko
  • Jerald S. Bradshaw
  • John D. Lamb
  • Peter Huszthy
  • Reed Izatt

Organizations

  • Brigham Young University

Tags

DTIC Thesaurus Topics

  • Alcohols
  • Amines
  • Amino Acids
  • Ammonium Picrate
  • Aqueous Solutions
  • Availability
  • Chemical Compounds
  • Chemical Synthesis
  • Chemistry
  • Chloroform
  • Coefficients
  • Crown Ethers
  • Ethers
  • Extraction
  • Macrocyclic Compounds
  • Recognition
  • Solvent Extraction

Fields of Study

  • Chemistry

Readers

  • Analytical Chemistry
  • Organic Chemistry