Identifying the Cognitive Decrements Caused By HIV
Abstract
This study had two purposes. The first was to determine the disease stage at which cognitive decrements caused by HIV become detectable. The second was to compare the sensitivity of information processing tests to neuropsychological instruments for detecting cognitive deficits caused by HIV. The study design initially had five groups: an asymptomatic group (Walter Reed Stages 1, 2, and 3), a symptomatic group (Walter Reed Stages 4 and 5), a homosexual, HIV-negative control group, a heterosexual, HIV-negative control group, and a group receiving anti-retroviral medication. After the data had been collected, the method of administering the Merieux, one of the staging criteria, was found to be unreliable. Consequently, the subjects were reclassified and the analyses focused on two groups: the asymptomatic group, which was now defined as subjects in either Walter Reed Stage 1 or 2, and the homosexual control group. Few differences were found between the two groups. The primary differences appeared to involve verbal fluency and verbal episodic memory. HIV, Neuropsychological assessment, Cognitive deficits, Information processing.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 10, 1994
- Accession Number
- ADA280961
Entities
People
- Alexandra M. Levine
- Diane L. Damos
- Elizabeth S. Parker
- Richard S. John
Organizations
- University of Southern California