World Reference Center for Arboviruses

Abstract

The World Reference Center for Arboviruses Characterized Sabia and Guanarito viruses, two new arenaviruses causing hemorrhagic fever in Brazil and Venezuela, respectively. A new genotype of Japanese encephalitis virus was discovered from Indonesia. Classifications of Venezuelan encephalitis and arenaviruses were revised. Outbreaks of arenavirus hemorrhagic fever in Venezuela and Brazil were investigated. Military watchdogs had antibody to Japanese encephalitis virus. Rapid PCR-based diagnostic techniques for encephalitides were developed. Neutralization tests of sera of army volunteers supported the licensing of the Japanese encephalitis inactivated vaccine. Recombinant vaccinia viruses expressing the prM/E genes were developed as candidate vaccines. Reagents were distributed to laboratories in 24 countries.

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Document Details

Document Type
Technical Report
Publication Date
Jun 07, 1994
Accession Number
ADA281635

Entities

People

  • Robert E. Shope

Organizations

  • Yale University

Tags

DTIC Thesaurus Topics

  • Arbovirus Infections
  • Arboviruses
  • Cells
  • Climate Change
  • Diseases And Disorders
  • Encephalitis
  • Epidemiology
  • Genetic Variation
  • Infectious Diseases
  • Medical Personnel
  • Proteins
  • Rift Valley Fever
  • Ticks
  • Vaccines
  • Virus Diseases
  • Viruses
  • Yellow Fever

Fields of Study

  • Biology

Readers

  • Virology (or Medical Virology).

Technology Areas

  • Biotechnology