Ultrashort Laser Pulse Effects in Ocular and Related Media: Laser-Induced Shock Wave Propagation and Retinal Damage.

Abstract

The goals of this project are: (1) To develop assays for functional damage to retinal cells by pressure waves (stress transients); (2) To determine the acoustic properties of the aqueous and vitreous humors of the eye; and (3) To examine the effect of pressure waves to the retinal pigment epithelium in vitro. During this first year our efforts have been directed primarily at the first goal, with some initial efforts on the second. During this period we developed the capability of growing human retinal pigment epithelium (RPE) cells in culture, incorporating them intest capillaries, recovering them after exposure to stress transients and assessing cell damage

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1994
Accession Number
ADA282599

Entities

People

  • A. G. Doukas
  • K. Dorey
  • Shang‐Fan Lee
  • T. F. Deutsch
  • T. Flotte

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • Acoustic Properties
  • Biological Pigments
  • Epithelium
  • Laser Pulses
  • Microvessels
  • Shock
  • Shock Waves
  • Wave Propagation
  • Waves

Readers

  • Atmospheric Science / Meteorology, specifically Wind Wave Turbulence.
  • Systems Analysis and Design
  • Vision Science/Vision Psychology/Cognitive Neuroscience.

Technology Areas

  • Directed Energy