World Reference Center for Arboviruses.
Abstract
The World Reference Center for Arboviruses received viruses from the United States and foreign countries for characterization and identification. New viruses, or viruses causing diseases not previously recognized included Sabia virus, a new arenavirus causing fatal hemorrhagic fever in Sao Paulo State, Brazil. Another arenavirus, Guanarito causes Venezuelan hemorrhagic fever, and was newly characterized. Venezuelan equine encephalitis, variety 1E, was for the first time recognized as epizootic in horses of Chiapas, Mexico. The confirmation of Rift Valley fever was made in Egypt during the return in 1993 of this disease of humans and domestic animals after an absence of 13 years. Recombinant vaccinia viruses were constructed to express proteins of, Japanese encephalitis (JE) and the four serotypes of dengue (DEN). Pigs were protected against viremia by arecombinant expressing JE preM/E as were mice by recombinants expressing YF and DEN preM/E. The low passage collection of arboviruses was augmented, and reference reagents were distributed to scientists in 21 countries
Document Details
- Document Type
- Technical Report
- Publication Date
- May 29, 1994
- Accession Number
- ADA283151
Entities
People
- Robert E. Shope
Organizations
- Yale University