Cardiorespiratory Changes During Microwave-Induced Lethal Heat Stress and Beta-adrenergic Blockade

Abstract

Sprague-Dawley rats were exposed to 2450-MHZ microwaves at an average power density of 60 mW/cm2 until lethal temperatures were attained. The effects of propanolol, nadolol, and labetalol on physiological responses were examined. Lethal temperatures in the labetalol and both propanolol groups were significantly lower than in saline controls. Respiratory rate was significantly elevated during most of the exposure period in animals given the high dose of propranolol. This respiration change is consistent with other studies of adrenergic blockade and may have been related to the shorter survival time in these animals. Microwaves, Body temperature, Heart rate, Respiration, Blood pressure.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1994
Accession Number
ADA283321

Entities

People

  • James R. Jauchem
  • Melvin R. Frei

Organizations

  • Armstrong Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Blood
  • Body Temperature
  • Cardiovascular Physiological Phenomena
  • Frequency
  • Health Services
  • Heart Rate
  • Hemorrhagic Shock
  • Medical Personnel
  • Microwaves
  • Physiology
  • Radiation
  • Radio Frequency
  • Respiration
  • Rodents
  • Skeletal Muscle
  • Survival
  • Temperature Gradients

Readers

  • Cardiovascular Physiology
  • Pulsed Power and Plasma Physics.
  • Toxicology/Environmental Toxicology