Use of Combination Thermal Therapy and Radiation in Breast Conserving Treatment of Extensive Intraductal Breast Cancer
Abstract
Year 01 of this contract supports the development of a technique for treatment of breast cancer, with an Extensive Intraductal Component (EIC) or pure Ductal Carcinoma in Situ (DCIS) using thermal therapy generated from ultrasound transducers. We have studied the technical approach for these treatments using complex computer simulations. The thermal treatment of the breast will be done with the patient in prone position with the breast submerged into a water filled applicator. A cylindrical array of individually controlled ultrasound transducers surround the breast. The cylindrical applicator consists of a stack of 10 rings, each being approximately 1.5 cm high. The ring located at the base of the breast contains 48 transducers. The number of transducers in each ring decrease toward the apex of the breast. Altogether there are 320 transducer elements requiring sophisticated computer control of power and frequency. The system is being built and subsystems are undergoing tests. Two clinical treatment protocols are currently being written; one for evaluation of the equipment treating approximately six patients and one for a larger Phase I/ II study. An IDE will be submitted to FDA in July 94. A work schedule for future year 02 and 03 is presented.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 11, 1994
- Accession Number
- ADA283964
Entities
People
- Everette C. Burdette
- Goran K. Svensson
Organizations
- Beth Israel Deaconess Medical Center