Strategies for the Control of Malaria
Abstract
The sexual stage of the parasite's life cycle takes place in the mosquito, which is its definitive host. Sporogony occurs in the mosquito's midgut following the ingestion of gametocytes from an infected human. The microgametocyte exflagellates to produce four to eight microgametes, each capable of fertilizing a macrogamete to form a zygote, which elongates to become a motile ookinete. These force their way through and between the epithelial cells to the outer surface of the midgut, where they round up into spheres called oocysts. An infected mosquito usually has one to ten oocysts
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1994
- Accession Number
- ADA285139
Entities
People
- G. T. Strickland
- S. L. Hoffman
Organizations
- Naval Medical Research Center