Progress Report for Contract Number N00014-93-C-0019 (Hawaii Biotechnology Group, Inc.)

Abstract

Production of anti-ferret sIgA antibodies. Status: Rabbit immunization completed. Immune serum collected. Cross-adsorbing rabbit serum and mouse ascites. Purification of lipopolysaccharide from Shigella and Campylobacter species. Status: Shigella LPS delivered to Navy. Collecting Campylobacter jejuni 81-176 cells for LPS extraction. Extraction method identified. Exploring alternative sources of Campylobacter LPS. Development of an enzyme immunoassay for the detection of enteroaggregative Escherichia coli heat-stable toxin. Status: This portion of the project has been suspended. Production of monoclonal antibodies against strain-specific antigenic epitopes on Campylobacter coli flagella. Status: Completed third fusion. No strain- specific MAbs identified. Discussing changes in protocol with NMRI researchers.

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Document Details

Document Type
Technical Report
Publication Date
Oct 31, 1994
Accession Number
ADA286274

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Adsorption
  • Antibodies
  • Bacterial Proteins
  • Biomedical And Dental Materials
  • Biotechnology
  • Cells
  • Chromatography
  • Contracts
  • Degradation
  • Environmental Pollutants
  • Escherichia Coli
  • Extraction
  • Guillain-Barre Syndrome
  • Immune Serums
  • Immunoglobulins
  • Polymeric Films
  • Proteins

Fields of Study

  • Biology

Readers

  • Immunology
  • Microbial Pathology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology