Flow through a Complaint Stenotic Artery: A Parametric Evaluation.

Abstract

Hardening of the arteries from atherosclerosis can produce high grade stenoses which lead to morbid symptoms of heart attack and stroke. Blood flow through the stenosis produces a low pressure zone at the throat which may cause the elastic artery to collapse. A one-dimensional model of collapsible tube flow through a smooth1 compliant stenoses was developed to evaluate the relative effects of several physiologic parameters. These variables included changes in percent stenosis, distal resistance, viscous separation losses, unsteady effects, stiffness variations, and non-linear tube law shapes. The range of variation attempted to bracket the conditions expected for diseased carotid and coronary arteries. The time-dependent equations were solved using MacCormack's method. Collapsed flow was more likely to be achieved with soft stenoses greater than 80% by diameter, low downstream resistances, and high external pressures. Collapsed flow was less likely to occur with stiff stenoses of less than 80% (dia) with a high distal resistance, large viscous losses, and a low external pressure. Pulsatile conditions resulted in situations where flow could alternate between supercritical and subcritical flow during the cycle. The results demonstrate that collapse of high grade stenotic arteries can occur under physiological conditions.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1993
Accession Number
ADA289701

Entities

People

  • J. M. Downing

Organizations

  • Armstrong Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Arteries
  • Blood Flow
  • Cardiovascular Physiological Phenomena
  • Cerebrovascular Disorders
  • Computational Fluid Dynamics
  • Computational Science
  • Computers
  • Embolism And Thrombosis
  • Equations
  • Equations Of State
  • Fluid Dynamics
  • Mechanical Properties
  • Mechanics
  • Myocardial Ischemia
  • Standing Waves
  • Two Dimensional

Readers

  • Cardiovascular Physiology
  • Electrical Engineering
  • Fluid Dynamics.