Support of the Center for Prostate Disease Research at Walter Reed Army Institute of Research.

Abstract

The Center For Prostate Disease Research (CPDR), a cooperative clinical and basic science research initiative focusing on prostate cancer and disease, began operations 14 September 1992 and this report summarizes the second year of operation. The CPDR is a research collaboration between the Uniformed Services University of the Health Sciences (USUHS), Walter Reed Army Medical Center (WRAMC) Urology Program, and the Armed Forces Institute of Pathology (AFIP) Genito-urinary Pathology Department. Regarding clinical research, a comprehensive prostate cancer patient database has been established with prospective data gathering on all patients from WAAMC. A retrospective database of all patients treated at WAAMC since 1980 is also underway. A serum and tissue bank for all prostate cancer patients at WAAMC has also been established. Regarding basic research, a fully equipped molecular biology laboratory has been established at USUHS for the exclusive study of the molecular genetics and cellular markers in prostate cancer and disease. The full collaborative cooperation between clinicians, clinical researchers, and basic scientists within CPDR has already been productive. The group has reported a commonly mutated region in the Androgen Receptor (AR) gene in advanced prostate cancer. Work is ongoing to determine the clinical significance of this genetic alteration. The CPDR group is excited and enthusiastic to continue with the clinical and basic research study of prostate cancer and disease within the DoD health care system and university.

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Document Details

Document Type
Technical Report
Publication Date
Oct 25, 1994
Accession Number
ADA289768

Entities

People

  • David G. Mcleod
  • Judd W. Moul

Organizations

  • Uniformed Services University of the Health Sciences

Tags

Communities of Interest

  • C4I

DTIC Thesaurus Topics

  • Androgen Receptors
  • Animals
  • Antineoplastic Agents
  • Biology
  • Day
  • Gene Therapy
  • Health Care
  • Health Services
  • Medical Personnel
  • Molecular Biology
  • Neoplasms
  • North America
  • Oncology
  • Prostate
  • Prostate Cancer
  • Recombinant Dna
  • Universities

Fields of Study

  • Medicine

Readers

  • Medical or Health Care Field.
  • Oncology
  • Research Science/Academic Research

Technology Areas

  • Biotechnology