Cardiovascular Control During Stimulated Hypergravity.

Abstract

A model of the circulation was developed using anesthetized dogs which allowed blood pressures and flows at different levels of the body to be changed in ways that simulated the events occurring during acceleration. In particular the responses were examined to decreases in pressure to the carotid baroreceptors and increases in pressure in the splanchnic circulation, changes that would occur during + Gz acceleration. Splanchnic congestion was found to elicit reflex vasoconstriction in the splanchnic. circulation itself as well as in the hind-limbs. There was an interaction between the effects of splanchnic distension and the carotid baroreceptor reflex resulting in nearly a doubling of the gain of the baroreflex. This research has defined a previously unknown mechanism which is likely to be of considerable importance in the maintenance of blood pressure during acceleration and could be of relevance to optimizing counter-G protection.

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Document Details

Document Type
Technical Report
Publication Date
Dec 22, 1994
Accession Number
ADA290919

Entities

People

  • Roger Hainsworth

Organizations

  • University of Leeds

Tags

Communities of Interest

  • Ground and Sea Platforms
  • Space

DTIC Thesaurus Topics

  • Animals
  • Arteries
  • Biological Sciences
  • Blood
  • Capacitance
  • Cardiovascular Diseases
  • Cardiovascular Physiological Phenomena
  • Cardiovascular System
  • Congestion
  • High Pressure
  • Laboratory Animals
  • Medical Personnel
  • Perfusion
  • Resistance
  • Veins
  • Vena Cava

Fields of Study

  • Medicine

Readers

  • Cardiovascular Physiology
  • Computational Modeling and Simulation