Detection and Clinicopathologic Correlation of Human Immunodeficiency Virus (HIV-1) Nucleic Acids and Antigens in Reticuloendothelial and Central Nervous System Tissues, by Immunohistochemistry, in Situ Hybridization, and Polymerase Chain Reaction.

Abstract

The initial goals of this project are to collect autopsy tissues from HIV-positive asymptomatic drug addicts who die unexpectedly from drug overdoses. A wide sampling of autopsy tissue will be subjected to various techniques in identifying and localizing HIV-1. The viral burden, cellular sites of replication and progression of viral disease will be studied.

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Document Details

Document Type
Technical Report
Publication Date
Dec 15, 1994
Accession Number
ADA291361

Entities

People

  • Allen P. Burke

Organizations

  • Armed Forces Institute of Pathology

Tags

DTIC Thesaurus Topics

  • Antigens
  • Central Nervous System
  • Chain Reactions
  • Chemical Reactions
  • Death
  • Detection
  • Diseases And Disorders
  • Hiv Infections
  • Laboratory Animals
  • Lymph Nodes
  • Lymphatic System
  • Materials
  • Nervous System
  • Nucleic Acids
  • Pathology
  • Polymerase Chain Reaction
  • Virus Diseases

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Child and Adolescent Substance Abuse Science in Autism Spectrum Disorders.
  • Molecular Genetics

Technology Areas

  • Biotechnology