A Discrete-Event Simulation Model of Myocardial Electrical Activity: Mathematical Electrophysiology.

Abstract

This work unit was opened to provide a channel for in-house work on mathematical modeling and computer simulation of the electrocardiogram (ECG) and its underlying electrophysiology. This work was intended to complement work being done in contracted efforts aimed at model-based enhancement of ECG diagnostic criteria for detection of coronary artery disease in USAF aircrew members. Both the contract and in-house efforts have been terminated due to funding constraints and organizational shifts in research focus. In this technical paper, we report on the development of a simulation model of the depolarization and repolarization processes in the ventricles which was to be used as a cardiac electrical source model in simulations of the ECG, as well as attempt to provide some commentary regarding the relation of these efforts to broader contexts.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1994
Accession Number
ADA292323

Entities

People

  • R. B. Howe

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Cardiovascular Diseases
  • Cardiovascular System
  • Computational Science
  • Computer Graphics
  • Computer Programming
  • Computer-Aided Design
  • Computers
  • Contracts
  • Depolarization
  • Electrophysiology
  • Health Services
  • Heart
  • Lists (Data Structures)
  • Mathematical Models
  • Myocardial Ischemia
  • Simulations
  • Waveforms

Readers

  • Cardiovascular Physiology
  • Computational Modeling and Simulation
  • Systems Analysis and Design