Cellular and Molecular Level Responses after Radiofrequency Radiation Exposure, Alone or in Combination with X-Rays or Chemicals.

Abstract

This project was initiated to explore the potential bioeffects of microwave radiation, alone or in combination with ionizing radiation and chemicals. Over the time period of the project, an automated thermal control system, to be used for maintaining the temperature in tissue culture medium during microwave exposures, was designed, constructed, and software was created. While this was underway during the project period, numerous positive control biological experiments were performed on two different cell types, the Epstein Barr Virus transformed 244B human lymphoblastoid cell, and the freshly isolated peripheral human lymphocyte. The 244B cells were used to address the question of whether a physical agent, ionizing radiation, at low doses where cells would predominantly remain viable, would induce the DNA binding protein NF-kB, and/or four immediate early genes (IEG) (protooncogenes).

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Document Details

Document Type
Technical Report
Publication Date
Feb 21, 1995
Accession Number
ADA292488

Entities

People

  • Adapa V. Prasad
  • Martin L. Meltz
  • Mohan Natarajan

Organizations

  • University of Texas Health Science Center at San Antonio

Tags

DTIC Thesaurus Topics

  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Gamma Rays
  • Genetics
  • Ionizing Radiation
  • Lymphocytes
  • Medical Personnel
  • Neoplasms
  • Peptide Growth Factors
  • Peptides
  • Proteins

Fields of Study

  • Biology

Readers

  • Molecular Biology and Genetics
  • Nuclear and Radiation Engineering.