Environmental Effects of Dredging, Initial Comparisons of Six Assays for the Assessment of Sediment Genotoxicity.

Abstract

This technical note reports and compares initial results of six genotoxicity bioassays applied to dredged sediments and describes progress toward development of a testing protocol to aid in regulatory decisionmaking when genotoxic chemicals are an issue of concern. The Long-term Effects of Dredging Operations Program work unit Genotoxicity of contaminated Dredged Material was initiated in fiscal year 1990 to develop methods for assessing the genotoxic potential of dredged sediments. The impetus driving this new research and development effort was specific regulatory language in section 103 of the Ocean Dumping Act (Marine Protection, Research, and Sanctuaries Act (MPRsA) of 1972) prohibiting the open-water discharge of mutagenic, carcinogenic, or teratogenic substances in other than trace amounts, and language less specific but of similar intent in section 404 of the Clean Water Act (CWA). pg1. JMD

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1995
Accession Number
ADA292604

Entities

People

  • Michael Honeycutt
  • Susan Jarvis
  • Victor A. Mcfarland

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Aquatic Organisms
  • Aromatic Hydrocarbons
  • Cancer
  • Cell Line
  • Cells
  • Culture Techniques
  • Cultured Cells
  • Materials
  • Mutagenicity Tests
  • Mutations
  • Neoplasms
  • Polychlorinated Biphenyls
  • Quality Control
  • Silica Gels
  • Test And Evaluation
  • Test Methods

Fields of Study

  • Environmental science

Readers

  • Coastal and Marine Engineering/Sediment Transport/Hydraulic Engineering
  • Government and Public Administration Law.
  • Toxicology/Environmental Toxicology