Study of the Effect of Hyperbaric Oxygen on Crush Injury in the Rat.

Abstract

When work commenced on this project according to the protocol, a device was constructed to drop a multi-kilo weight through a distance of up to one meter so that it would produce a crushing injury to a rat tail. When this was initially tried, it was found that injury was not predictable, as sometimes vertebrae would be crushed, injuring the ventral artery, causing a complete loss of the tail. It the ventral artery were not damaged, the tail survived without appreciable injury. It was also noted that tissues of the tail contained mostly tendon and very little muscle. Following this, the crushing agent was modified to traumatize a musculocutaneous flap which was raised on the rat's back.

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Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1993
Accession Number
ADA294128

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  • Eric Kindwall

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  • Medical College of Wisconsin

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  • Biomedical

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