The Efficacy of Cyanoacrylates in the Primary Closure of Conjunctival-Schleral Lacerations.
Abstract
We designed a study to evaluate the efficacy of cyanoacrylate adhesive (CA) in the temporary closure of scleral lacerations. Ocular injuries are expected to comprise up to 10% of total casualties on the modern battlefield and would overwhelm the limited medical facilities near front lines. An expedient method of stabilizing open eyes is needed. A 6 mm laceration was created 3 mm posterior to the limbus in albino rabbits. The animals were randomized into three groups: standard closure with sutures (13), closure with CA (28), or untreated (21). The animals were euthanized at 2 days, 1, 2, 4, and 8 weeks. On histopathologic examination, a fibrous bridge was noted in all animals by 2 weeks. Prior to fibrous bridge formation, intraocular pressures (lOP's) and dark- adapted electroretinogram (ERG) a- - and b-wave amplitudes were lower in open eyes compared to those in which wounds were surgically closed using CA or- suture.- - Flare was increased in open eyes. The clinical course- of the CA-group'compared favorably with eyes closed by -the standard suture technique. - This study supports the efficacy of - using cyanoacrylate adhesive as a temporary, expedient method of closing scleral lacerations.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 15, 1995
- Accession Number
- ADA296763
Entities
People
- Brian Cavallaro
- Fleming Wertz
- Rodney Hollifield
- Thomas Ward
Organizations
- Walter Reed Army Medical Center