Subchronic Toxicity Studies on 1,3,5-Trinitrobenzene, l,3-Dinitrobenzene, and Tetryl in Rats.

Abstract

Nitroaromatics, such as 1 ,3-dinitrobenzene (DNB), 1 ,3,5-trinitrobenzene (TN B), and N-methyl-N,2,4,6-tetranitroaniline (tetryl), have been detected as environmental contaminants of groundwater and soil near production sites and in some instances at military test grounds. DNB is formed as a by-product during 2,4,6-trinitrotoluene (TNT) production. It is also formed through photochemical oxidative degradation of 2,4- dinitrotoluene a by-product released into the environment from TNT manufacturing (Spanggord et.al., 1980). DNB and TNB are not easily biodegradable, persist in the environment, eventually leach out, and contaminate groundwater near waste disposal sites. Tetryl is an explosive that has been in use, largely for military purposes, since 1906. Wastewaters and soil at the original production sites and other plants devoted to munitions assembly, contain large quantities of these compounds (Walsh and Jenkins, 1992).

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1995
Accession Number
ADA297458

Entities

People

  • B. Wiechman
  • F. B. Daniel
  • G. R. Olson
  • Michael Robinson
  • Tirumuru V. Reddy

Organizations

  • Environmental Protection Agency

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood
  • Blood Cells
  • Blood Proteins
  • Body Weight
  • Cell Count
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Environmental Protection
  • Erythroid Cells
  • Hematology
  • Hemoglobin
  • Leukocytes
  • Medical Personnel
  • Rodents
  • Sex Glands

Fields of Study

  • Environmental science

Readers

  • Agricultural Chemistry/Soil Science
  • Systems Analysis and Design