A Comprehensive Repository of Normal and Tumor Human Breast Tissues and Cells.
Abstract
The development of breast cancer is likely to be a multi-step, progressive process with several heritable alterations accumulated during the evolution to malignancy. Since one of the major objectives of breast cancer research is to provide a means for early intervention, it is important to define the specific molecular alterations at each stage in this process. The study of such alterations is greatly aided by having not only tumor cells but also corresponding non-malignant breast cells of stromal and epithelial origin. We have established a unique repository of materials for the biologic and genetic study of breast cancer. The repository contains cryopreserved and cultured cells from tumor tissues, non-malignant epithelial and stromal cells and when available peripheral blood mononuclear cells. Patient demographic and clinical data, and family history are collected and entered onto a relational database.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 12, 1995
- Accession Number
- ADA299278
Entities
People
- Jerry W. Shay
Organizations
- University of Texas at Dallas