Human Immune Responses to Experimental Vaccinia Vaccines.
Abstract
Members of the U.S. Armed Forces receive immunization with vaccinia virus vaccine. Efforts to develop a safe and effective tissue culture-derived vaccinia vaccine to replace the standard vaccine produced by scarification on cows' skin have advanced early clinical studies. It is generally accepted that protection induced by the conventional vaccinia vaccine correlated with cellular immune responses. The I purpose of this research program is to measure human cellular and humoral immune responses to live experimental and standard vaccinia vaccines.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1995
- Accession Number
- ADA299784
Entities
People
- Francis A. Ennis
- Walter E. Demkowicz
Organizations
- University of Massachusetts