Development of Ligand-Transformed Alpha-Fetoprotein for Use Against Breast Cancer in Humans.

Abstract

Human alpha-fetoprotein (hAFP) upon incubation with sex steroid hormones is chemically converted into an inhibitor of estrogen-dependent breast cancer growth. This document describes the progress which was made during the first year of a research grant which was designed to develop the active form of hAFP as a treatment for breast cancer and establish markers which both predict and monitor breast cancer responsiveness to this form of AFP.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1995
Accession Number
ADA299826

Entities

People

  • James A. Bennett

Organizations

  • Albany Medical College

Tags

DTIC Thesaurus Topics

  • Autoimmune Diseases
  • Baculoviridae
  • Breast Cancer
  • Cell Line
  • Cell Physiological Processes
  • Cells
  • Cellular Structures
  • Chemistry
  • Clinical Trials
  • Culture Techniques
  • Hormones
  • Materials
  • Medical Personnel
  • Molecules
  • Neoplasms
  • Tumor Cell Line
  • Vitamin D

Readers

  • Breast cancer cell signaling and growth regulation.
  • Oncology (Cancer Research).