Environmental Effects of Dredging: Methods for the Assessment of the Genotoxic Effects of Environmental Contaminants; Cellular and Organ/Organism Effects
Abstract
This technical note is the second in a series of three that outline and describe the principal methods that have been developed to test the potential of environmental contaminants for causing mutagenic, carcinogenic, and teratogenic effects. The first in this series (EEDP-04-24) describes methods used to discern genotoxic effects at the subcellular level, while this technical note describes methods used to discern genotoxic effects at the cellular and organ/ organism level. Recent literature citations for each topic are listed in the third technical note (EEDP-04-26) to assist readers in locating source information. A glossary of terms is also provided in Technical Note EEDP-O4-26. The information in these technical notes is intended to provide Corps of Engineers personnel with a working knowledge of the terminology and conceptual basis of genotoxicity testing. To develop an improved understanding of the concepts of genotoxicity, readers are encouraged to review "A Primer in Genotoxicity" (Farvis, Reilly, and Lutz 1993), presented in Volume D-933 of the Environmental Effects of Dredgtng information exchange bulletin.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jul 01, 1995
- Accession Number
- ADA299850
Entities
People
- A. S. Jarvis
- Michael E. Honeycutt
- Victor A. Mcfarland