Final Technical Report for Contract N00014-91-J-1764 (Columbia College).
Abstract
This study describes hippocampal participation in classical conditioning in terms of a multilayer network that portrays stimulus configuration. The network (a) describes behavior in real time, (b) incorporates a layer of "hidden" units positioned between input and output units, (c) includes inputs that are connected to the output directly as well as indirectly through the hidden-unit layer, and (d) employs a biologically plausible backpropagation procedure to train the hidden-unit layer. The model correctly describes the effect of hippocampal and cortical lesions in the following paradigms: (1) acquisition of delay and trace conditioning, (2) extinction, (3) acquisition-extinction series of delay conditioning, (4) blocking, (5) overshadowing, (6) discrimination acquisition, (7) discrimination reversal, (8) feature-positive discrimination, (9) conditioned inhibition, (10) negative patterning, (11) positive patterning, and (12) generalization. Some of these results might be extended to the description of anterograde amnesia in human patients.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jan 01, 1995
- Accession Number
- ADA300494
Entities
People
- Geog Goldbogen
- Nestor A. Schmajuk
- Zafra Lerman
Organizations
- Columbia University