Evaluation of Flow Biosensor Technology in a Chronically-Instrumented Non-Human Primate Model,

Abstract

The Physiology Research Branch of Brooks AFB conducts both human and non-hiuman primate experiments to determine the effects of microgravity and hypergravity on the cardiovascular system and to indenti% the particular mechanisms that invoke these responses. Primary investigative research efforts in a non-human primate model require the calculation of total peripheral resistance (TPR), systemic arterial compliance (SAC), and pressure-volume loop characteristics. These calculations require beat-to-beat measurement of aortic flow. We have evaluated commercially available electromagnetic (EMF) and transit-time flow measurement techniques. In vivo and in vitro experiments demonstrated that the average error of these techniques as less than 25 percent for EMF and less than 10 percent for transit4ime.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1995
Accession Number
ADA300623

Entities

People

  • C. Reister
  • G. Muniz
  • J. Schraub
  • S. C. Koenig
  • T. Fergusan

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Aerospace Medicine
  • Animals
  • Arteries
  • Biomedical Engineering
  • Biosensors
  • Blood Flow
  • Cardiovascular System
  • Engineering
  • Errors
  • Flow
  • Flow Rate
  • Laboratory Animals
  • Magnetic Fields
  • Measurement
  • Resistance
  • Rhesus Monkeys
  • Test And Evaluation

Readers

  • Cardiovascular Physiology
  • Computational Modeling and Simulation

Technology Areas

  • Biotechnology