P53 Mutation Profiles in Premenopausal Versus Breast Cancer in a Stationary Population.

Abstract

There is a difference in profiles of p53 mutation in pre and post menopausal breast cancers. Mutation of the p53 gene is often in exon 5 for postmenopausal breast cancer but mutation of p53 is often in exon 6 and 7 for premenopausal breast cancers, therefore p53 may be a useful epidemiological tool for identification of mutagen and genetic factors that contribute to breast cancer.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1995
Accession Number
ADA302430

Entities

People

  • Bao-fu Yu

Organizations

  • Salk Institute for Biological Studies

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Breast Cancer
  • Cancer
  • Cells
  • Chemical Reactions
  • Diseases And Disorders
  • Genes
  • Genetics
  • Identification
  • Materials
  • Medical Personnel
  • Mutagens
  • Mutations
  • Neoplasms
  • Polymerase Chain Reaction
  • Stationary

Fields of Study

  • Biology

Readers

  • Oncology
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology