Low Molecular Weight Leachables From Medical Grade Polymers,
Abstract
Four medically important polymeric materials (silicone polymer from mammary prostheses, polyurethane, polyethylene, and polycarbonate) were placed in contact with water for time periods ranging from four hours to seven days. Substances leaching into water were separated by extraction with methylene chloride, or by evaporation of water, and identification of species in the leachate was attempted by a number of analytical techniques, with extensive use of combined gas chromatography/mass spectrometry (GC/MS). Low molecular weight fragments of dimethylsiloxane were identified from mammary prosthesis gel. Spectra are also included for leachate from the other three polymers; identification of these compounds is still in process.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1982
- Accession Number
- ADA303001
Entities
People
- B. F. Howell
- D. J. Reeder
- L. Hilpert
- S. Chesler
Organizations
- National Institute of Standards and Technology