Support for HIV-1 Intervention Therapy.

Abstract

Since 1992 SRA Technologies, Inc. has provided services in support of DoD interventional trials for HIV. Three working groups were established in the areas of molecular biology, cellular phenotyping and drug testing. Production level services were provided for virus isolation, expansion, titration, sequencing, mutational analysis and drug susceptibility testing. Significant progress was made in the development of new assays for drug resistance, antibody neutralization, mutational analysis and for efficacy analysis of suggested by the discovery df factors from CD3/CD28 antibody stimulated cells that inhibit HIV Infection in Vitro.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1995
Accession Number
ADA303127

Entities

People

  • Owen S. Weislow

Tags

DTIC Thesaurus Topics

  • Anti-Infective Agents
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Computer Programming
  • Computers
  • Culture Techniques
  • Hiv Infections
  • Infection
  • Information Systems
  • Local Area Networks
  • Lymphatic System
  • Lymphocytes
  • Medical Personnel
  • Molecular Biology
  • Proteins
  • Viruses

Fields of Study

  • Biology

Readers

  • Defense Acquisition Program Management
  • Infectious Disease/Epidemiology
  • Molecular and Cellular Biology