Blood Amplification: Use of Phosphoenolpyruvate (PEP) Treated Red Blood Cell Transfusions in the Dog (Canis familiaris).

Abstract

Theoretically, decreasing hemoglobin oxygen affinity (HOA) of red blood cells (RBC) prior to transfusion should augment oxygen consumption during anemic hypoxia. Incubation of RBCs with phospenolpyruvate (PEP) increases 2,3-DPG and decreases HOA. This study evaluated the effect of transfusion with PEP treated RBCs on cardiovascular compensation and oxygen consumption in acutely anemic dogs.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1996
Accession Number
ADA306015

Entities

People

  • Rhonda L. Cornum

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Amplification
  • Animals
  • Arteries
  • Availability
  • Blood
  • Blood Cells
  • Blood Transfusions
  • Cells
  • Hematocrit
  • Hemorrhage
  • Materials
  • Monitoring
  • Recombinant Dna
  • Standards
  • Veins
  • Vital Signs

Readers

  • Cardiovascular Physiology
  • Electronics Engineering
  • Immunology