Dose-Response Correlation of Methadone and its Metabolite EDDP in Human Hair. Start of the Third Series and Analysis of the Samples of the Second Test Series.

Abstract

We were able to arrange for the patients of two further Methadon practices, that of Dr. Sachtleben in Pirmasens and Dr. Lueg in Kaiserslautem, to take part in our study. They were treated in the same manner as described in our previous Technical Reports. In this new series, the applied sweat patches were generally well accepted. Up until now only one patient (L2) has complained about irritations from the last patch. Blood was drawn by the personnel of the two practices. Hair strands were cut and bleached in the same manner as described previously. One patient from Kaiserslautem agreed only to give sweat and blood samples, another quit the program after collection of sweat patches and bleaching and cutting of the first hair strand. Nevertheless, this subject could be convinced to give blood and a small hair sample from the bleached strand to evaluate her individual hair growth window.

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Document Details

Document Type
Technical Report
Publication Date
Mar 31, 1996
Accession Number
ADA309800

Entities

Organizations

  • United States Naval Research Laboratory

Tags

DTIC Thesaurus Topics

  • Alcohols
  • Chemical Properties
  • Contracts
  • Diseases And Disorders
  • Drug Abuse
  • Extraction
  • Irritation
  • Metabolites
  • Methadone
  • Methanols
  • Molecules
  • Organic Solvents
  • Solvents
  • Test And Evaluation

Fields of Study

  • Medicine

Readers

  • Parasitology and Pharmacology of Malaria.
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology