Detection and Characterization of Genetic Alterations on Chromosome 16 for Breast Cancer.

Abstract

This grant funded a Special Sabbatical for research in breast cancer for one year. There were two principle tasks in this grant; the first was to localize a potential tumor suppressor gene on chromosome 16 and the second was to further develop the molecular biology skills of the investigator. The research project continues to be in progress as we are at the stage of the secondary screening of a normal breast cell cDNA library and are preparing to sequence the DNA. In addition to this project, two additional studies were initiated, evaluating the effects of estrogen and progesterone on breast cancer cells.

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Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1996
Accession Number
ADA310545

Entities

People

  • Rosemary B. Duda

Organizations

  • Beth Israel Deaconess Medical Center

Tags

DTIC Thesaurus Topics

  • Breast Cancer
  • Cell Line
  • Cells
  • Cellular Structures
  • Chemical Synthesis
  • Chemistry
  • Chromosomes
  • Diseases And Disorders
  • Estrogens
  • Gene Expression
  • Genetic Structures
  • Health Services
  • Hormones
  • Medical Personnel
  • Molecular Biology
  • Mrna
  • Neoplasms

Fields of Study

  • Biology

Readers

  • Molecular Genetics
  • Research Science/Academic Research
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.

Technology Areas

  • Biotechnology
  • Biotechnology - Cancer Biotech