Phytoestrogens in the Food Supply.

Abstract

Endogenous estrogens are thought to have a role in the etiology of breast cancer. Several components of plant foods have estrogenic activity or are metabolized to active compounds by mammalian systems (phytoestrogens). The impact of these constituents on breast cancer risk is unknown because of the lack of databases containing appropriate values for foods. The goal of this research is to provide a database of values for the various isoflavones (one family of phytoestrogens) in soy-based foods and commodities. Six critical research components have been identified: (1) develop and validate rugged analytical procedures, (2) establish appropriate analytical quality control system, (3) identify commonly consumed soy-based foods and commodities, (4) develop food sampling scheme for each food or commodity, (5) prepare and analyze foods, and (6) develop critical data evaluation system and prepare database of values. Research components one through three have been completed. Several foods have been sampled, based on appropriate sampling schemes, prepared and analyzed. Additional foods will be sampled and analyzed as food sales information is received. The data evaluation system currently is being modified to accept and review isoflavone data. When all data have been entered into this system, a database of isoflavone values complete with food names and codes will be produced.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1996
Accession Number
ADA311388

Entities

People

  • Gary R. Beecher

Organizations

  • United States Department of Agriculture

Tags

DTIC Thesaurus Topics

  • Artificial Intelligence
  • Breast Cancer
  • Cell Line
  • Cells
  • Chemistry
  • Control Systems
  • Databases
  • Detectors
  • Diseases And Disorders
  • Enzyme Inhibitors
  • Estrogens
  • Fungi
  • Liquid Chromatography
  • Medical Personnel
  • Neoplasms
  • Prostate Cancer
  • Quality Control

Readers

  • Computational Modeling and Simulation
  • Industrial Economics
  • Molecular Biology and Genetics