Genetic Engineering of Polymers Containing Non-Natural Amino Acids.
Abstract
The goal of this research program has been to establish strategies for producing protein-based materials that contain amino acids not normally found in natural proteins. Efforts have been focused on amino acids with fluorinated, electroactive or conformationally constrained side chains, and have allowed us to prepare protein-based polymers with unique properties, including low surface energies and sensitivity to electrochemical signals. These developments have expanded in a substantial way the range of materials properties accessible via chemical or biological synthesis of polypeptides and artificial proteins.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1996
- Accession Number
- ADA313717
Entities
People
- David A. Tirrell
Organizations
- University of Massachusetts Amherst