A Comprehensive Repository of Normal and Tumor Human Breast Tissue and Cells.

Abstract

The development of breast cancer is likely to be a multi-step progressive process with several heritable alterations accumulated during the evolution to malignancy. In order to have surrogate endpoint markers to provide a means for early intervention, it is important to define the specific molecular alterations at each stage of this process. The study of such alterations should be greatly facilitated by having not only cells derived from breast tumors but also corresponding non-malignant breast cells of stromal and epithelial origin. We have successfully established a unique repository which contains cryopreserved and cultured cells from human breast tumor tissues, non-malignant breast epithelial and stromal cells and peripheral blood mononuclear cells.

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Document Details

Document Type
Technical Report
Publication Date
Jul 01, 1996
Accession Number
ADA314090

Entities

People

  • Jerry W. Shay

Organizations

  • University of Texas at Dallas

Tags

DTIC Thesaurus Topics

  • Breast Cancer
  • Cancer
  • Carcinoma
  • Cell Line
  • Cells
  • Culture Techniques
  • Cultured Cells
  • Databases
  • Diseases And Disorders
  • Materials
  • Medical Personnel
  • Neoplasms
  • Storage
  • Stromal Cells
  • Tumor Cell Line

Fields of Study

  • Medicine

Readers

  • Immunology
  • Molecular and genetic basis of cancer.