Electrically Mediated Trauma Repair.

Abstract

In the second year of this contract period we have made substantial progress in experiments designed to facilitate recovery of functions following severe acute spinal cord injury in the adult mammal. The intervention is through the use of applied voltage gradients. We have shown that this technique can be used in conjunction with polymeric tubes to induce and guide regenerating axons. We have also developed novel two and three-dimensional reconstruction techniques and morphometry to assay our biological responses to treatment between control and experimental groups. Using these, we have assayed the level of macrophage infestation of acute and subacute spinal cord injuries.

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Document Details

Document Type
Technical Report
Publication Date
Sep 01, 1996
Accession Number
ADA315230

Entities

People

  • Richard B. Borgens

Organizations

  • Purdue Research Foundation

Tags

DTIC Thesaurus Topics

  • Animals
  • Biomedical Research
  • Cells
  • Computers
  • Contracts
  • Geometry
  • Histological Techniques
  • Macrophages
  • Phagocytes
  • Rodents
  • Soft Tissues
  • Spinal Cord
  • Spinal Injuries
  • Surgery
  • Three Dimensional
  • Two Dimensional
  • Wounds And Injuries

Fields of Study

  • Medicine

Readers

  • Neuroscience
  • Toxicology/Environmental Toxicology
  • Trauma Surgery or Emergency Medicine.