Breast Cancer Incidence in Occupational Cohorts Exposed to Ethylene Oxide and Polychlorinated Biphenyls.

Abstract

NIOSH is evaluating breast cancer incidence in two large study cohorts, which have been previously assembled. One of the cohorts includes approximately 10,000 women with exposure to ethylene oxide (ETO), a direct alkylating agent which produces mammary tumors in mice. The other cohort includes over 13,000 women exposed to polychlorinated biphenyls (PCBs), a group of chemicals suspected to be carcinogenic to the breast because of their lipophilic and estrogenic activities. Each cohort represents the largest and best defined female study cohort in the U.S. for the respective exposure. The primary activities for this year have focused on establishing vital status and mailing addresses for individuals in the two study cohorts, and seeking OMB approval for the study questionnaires. Work to accomplish vital status and address identification is proceeding in a timely fashion. OMB approval was received in April of 1996

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1996
Accession Number
ADA315695

Entities

People

  • Elizabeth M. Ward

Organizations

  • National Institute for Occupational Safety and Health

Tags

DTIC Thesaurus Topics

  • Alkenes
  • Alkylating Agents
  • Animals
  • Biphenyl
  • Breast Cancer
  • Cancer
  • Carcinogens
  • Ethylene Oxide
  • Ethylenes
  • Health Services
  • Laboratory Animals
  • Neoplasms
  • Oxides
  • Polychlorinated Biphenyls
  • Questionnaires
  • Risk Factors
  • Surveys

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