Nature and Prognostic Significance of Alterations in the DCC and E-Cadherin Genes in Breast Cancer.

Abstract

In the original application, three technical objectives were proposed with the goal of understanding the role of the adhesion molecules DCC and E-cadherin in breast cancer. The initial task focused on use of LOH to assist in confirming that these adhesion molecules are important in the pathogenesis of breast cancer. Ultimately, the long term goals were to apply the findings of these studies to improving the diagnosis and management of breast cancer.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1996
Accession Number
ADA317876

Entities

People

  • David L Rimm

Organizations

  • Yale University

Tags

DTIC Thesaurus Topics

  • Breast Cancer
  • Carcinoma
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Genetic Structures
  • Genetics
  • Health Services
  • Intercellular Junctions
  • Medical Personnel
  • Oncology

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