Enhanced Trichloroethylene Degradation Using Genetically-Engineered Microorganisms.

Abstract

Novel recombinant TCE-degrading bacteria were created using the best known enzyme for TCE degradation, soluble methane monooxygenase(sMMO) of the soil bacterium Methylosinus trichosporium OB3b. sMMO degrades a wide range of halogenated hydrocarbons (HCFCs, chloroform, dichloroethane, etc.), and it degrades TCE 100 times faster than any other microbial enzyme. The mmo genes were cloned and expressed in Pseudomonas putida Fl, Agrobacterium tumefaciens, and Rhizobium meliloti using plasmids pSMMO20 and pSMMO40 created by the Wood laboratory. In addition, a novel fixed-film bioreactor has been constructed and optimized to mineralize TCE in the gas phase.

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Document Details

Document Type
Technical Report
Publication Date
Dec 28, 1996
Accession Number
ADA321121

Entities

People

  • Thomas K. Wood

Organizations

  • University of California, Irvine

Tags

Communities of Interest

  • Human Systems

DTIC Thesaurus Topics

  • Bacteria
  • Biochemical Engineering
  • Bioengineering
  • Bioreactors
  • Biotechnology
  • Chemical Engineering
  • Chloroform
  • Degradation
  • Engineering
  • Engineers
  • Halogenated Hydrocarbons
  • Hydrocarbons
  • Microbiology
  • Microorganisms
  • Pseudomonas Infections
  • Synthetic Biology
  • Waste Management

Fields of Study

  • Biology
  • Engineering
  • Environmental science

Readers

  • Analytical Chemistry
  • Fire Suppression Systems Design.
  • Molecular Genetics

Technology Areas

  • Biotechnology
  • Biotechnology - Bioremediation