Linkage of Molecular and Epidemiological Breast Cancer Investigations with Treatment Data: A Specialized Registry.

Abstract

During year two of this project, the Cancer and Leukemia Group B (CALGB) entered 40 breast cancer patients into the Linked Registry according to procedures specified in CALGB Protocol 9484. The telephone interviews of patients have gone smoothly and the entry of data from the interviews by the CALGB Data Management Center has been free of problems. The flow of patient samples from CALGB 9484 has begun and the storage of samples and preparation of DNA has been problem free. The number of institutions participating in the project has been limited by the actions of IRBs many of which have disapproved the protocol because of concerns about the risks of genetic testing. In view of this, the protocol has been amended in a manner that will reduce or eliminate concern about this issue and to improve the efficiency of patient entry. A Certificate of Confidentiality has been granted to this project further reducing the risk to patients contributing samples for studies of genomic DNA.

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Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1996
Accession Number
ADA322444

Entities

People

  • O. R. Mcintyre

Organizations

  • Dartmouth College

Tags

DTIC Thesaurus Topics

  • Blood
  • Breast Cancer
  • Cancer
  • Clinical Trials
  • Databases
  • Diseases And Disorders
  • Epidemiology
  • Families (Human)
  • Genetic Testing
  • Genetics
  • Health Services
  • Institutional Review Board
  • Medical Personnel
  • Neoplasms
  • Oncology
  • Ovarian Cancer
  • Physicians

Readers

  • Clinical Trial Research.
  • Molecular and genetic basis of cancer.
  • Systems Analysis and Design

Technology Areas

  • Biotechnology