Investigations in Fish Control. 98. History of Acute Toxicity with Fish, 1863-1987.

Abstract

Acute toxicity tests with fish were first reported in 1863. Test methodology developed slowly before World War II, during the period when the goldfish (Carassius auratus) was the recommended test animal. After the war, considerable effort was made to standardize test methods. A standardized method was published in 1960, refined in 1975, and updated in 1980. The primary use of the static acute toxicity test is to determine the median concentrations of chemicals that are lethal to aquatic organisms. Other applications include establishing the half-life of the biological activity of chemicals, evaluating the toxicity of mixtures of chemicals, and developing quantitative structure activity relations used in predicting the toxicity of particular groups of chemicals.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1989
Accession Number
ADA322662

Entities

People

  • Joseph B. Hunn

Organizations

  • United States Fish and Wildlife Service

Tags

DTIC Thesaurus Topics

  • Chemical Synthesis
  • Chemistry
  • Environmental Protection
  • Fish
  • Fisheries
  • Health Services
  • Public Health
  • Test Methods
  • Waste Products
  • Wildlife

Fields of Study

  • Environmental science

Readers

  • Aquatic Ecology
  • Computational Modeling and Simulation
  • Toxicology/Environmental Toxicology