Preparation of Chemicals and Bulk Drug Substances for the U.S. Army Drug Development Program.

Abstract

The purpose of the contract is to provide a variety of high purity chemicals and bulk drug substances for the U.S. Army Medical R & D Command. During the 12 months, eighteen assignments were completed. Compounds prepared and submitted include the antimalarial WR 238605, one metabolite of WR 238605, four potential metabolites of WR 242511, four pyridinecarbamates, one substituted benzenesulfonamide, two benzenesulfonyl chlorides, and a 3-deazapurine. In addition, racemic desbutylhalofantrine and WR 242511 were resolved to provide samples of the optically active enantiomers.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1996
Accession Number
ADA323200

Entities

People

  • Peter Blumbergs

Tags

DTIC Thesaurus Topics

  • Chemical Compounds
  • Chemical Synthesis
  • Chemistry
  • Ethers
  • Hydroxides
  • Liquid Chromatography
  • Organic Chemistry
  • Sodium Compounds

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry
  • Parasitology and Pharmacology of Malaria.