Real-Time Monitoring and Control Methodologies to Aid in the Study of Protein Interactions for Biosensor Applications.

Abstract

There is an emergent need for portable, inexpensive, reusable, and reliable sensors of environmental contaminants for both military and civilian uses. The development and study of such sensors is crucial for many applications. Among others, we mention measuring groundwater and waste water contamination, monitoring processes for agricultural and food products, and detecting soil contamination. In addition, such a technology is key to many medical procedures. The use of these sensors may be required on a continual and/or on a regular basis. In that respect, optically based sensors of protein interactions-such as those utilizing the optical phenomenon of Surface Plasmon Resonance (SPR)-show promise in producing sensory systems that are reusable, precise and portable for a range of applications. This proposal is to develop a computing platform to be used in the real-time monitoring, studying, and control of protein interactions. In particular, this platform allows the adaptive control of biosensor devices by integrating various data analysis and decision support modules, which could be used in a real-time fashion to control on-going experiments or synthesize and schedule new experiments in a distributed environment.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1997
Accession Number
ADA324875

Entities

People

  • Azer Bestavros

Tags

Communities of Interest

  • Biomedical
  • Materials and Manufacturing Processes

DTIC Thesaurus Topics

  • Biosensors
  • Contamination
  • Data Analysis
  • Detectors
  • Environment
  • Environmental Pollutants
  • Monitoring
  • Platforms
  • Resonance
  • Surface Plasmon Resonance
  • Surface Plasmons
  • Waste Water
  • Water

Readers

  • Distributed Systems and Data Platform Development
  • Environmental Engineering
  • Technical Research and Report Writing.

Technology Areas

  • Biotechnology