Regulation of the Estrogen Structural Gene in Breast Tissue by the AH Receptor.

Abstract

The objectives of this research are three-fold: (1) to determine the cell- and developmentally related expression and activation of the AhR in rat mammary tissue, (2) to examine the ability of AhR agonists to affect the expression of the ER in mammary tissue; and (3) to examine the mechanism by which the AhR down regulates the expression of the ER structural gene.

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Document Details

Document Type
Technical Report
Publication Date
Aug 01, 1996
Accession Number
ADA325810

Entities

People

  • Thomas A. Gasiewicz

Organizations

  • University of Rochester

Tags

DTIC Thesaurus Topics

  • Aromatic Hydrocarbons
  • Body Weight
  • Breast Cancer
  • Cells
  • Chemical Compounds
  • Chemical Synthesis
  • Chemistry
  • Environmental Health
  • Estrogens
  • Growth Factors
  • Laboratory Animals
  • Molecular Dynamics
  • Organic Chemistry
  • Rodents
  • Tumor Cell Line

Readers

  • Battery Technology and Engineering
  • Molecular Biology and Genetics