Molecular Detection of Breast Cancer.
Abstract
This project is designed to develop novel approaches to detect breast cancer cells that contaminate peripheral blood and bone marrow, and to remove such contaminating cells. An RT-PCR assay has been developed to detect breast cancer cells, and a novel gene therapy vector has been developed to kill contaminating cancer cells. Blood and bone marrow samples obtained from patients with breast cancer are being collected. These samples will be analyzed to determine whether the Kl9 RT-PCR assay can be used to predict outcome. Next, a gene therapy vector, the bcl-xs adenovirus, has been developed.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1997
- Accession Number
- ADA326076
Entities
People
- Michael F Clarke
Organizations
- University of Michigan