Spatial Distribution of the EGF Receptor in Regulation of Breast Epithelial Cell Growth and Organization.

Abstract

An important goal of current breast cancer research is to develop an in vitro system that can define the mechanisms involved in the progression of human mammary epithelial cells (HMEC) towards a transformed phenotype. In this project, we have focused on an aspect of HMEC behavior that is likely to be involved in this progression, namely, the correct spatial sorting of growth factors and their receptors to discrete cellular locations.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Mar 01, 1997
Accession Number
ADA327081

Entities

People

  • H. S. Wiley

Organizations

  • University of Utah

Tags

DTIC Thesaurus Topics

  • Biomedical Research
  • Breast Cancer
  • Cell Movement
  • Cell Physiological Processes
  • Cells
  • Chemistry
  • Confocal Microscopy
  • Diseases And Disorders
  • Epithelial Cells
  • Growth Factors
  • Mammary Glands
  • Microscopy
  • Neoplasms
  • Peptide Growth Factors
  • Polymerase Chain Reaction
  • Proteins
  • Spatial Distribution

Fields of Study

  • Biology

Readers

  • Coastal Oceanography
  • Molecular Biology and Genetics