Protective Immunity to Hepatitis B and Streptococcus Pneumoniae in Active Duty Women Versus Men: Prevalence and Response to Preventive Immunization.

Abstract

Women in the military may have an increased occupational of hepatitis B infection. There is currently on clear data available regarding differences in duration of vaccine response between men and women. This study will provide data regarding the prevalence of protective immunity among active duty women in different age groups, under the current guidelines of immunization practice. In addition, a cost-effective vaccine booster strategy will be compared to the standard 1.0 ml dose of vaccine. Since pneumonia among military recruits is caused by S. pneumoniae, data on the prevalence of natural immunity in active duty women would be helpful for future planning of more effective immunization strategies. Using a health assessment questionnaire, serum samples and anergy skin testing, subjects will be screened for eligibility and assessed to determine protective antibody levels to hepatitis B and S: pneumoniae. We suspect there is a difference-between women and men in antibody response from immunization to hepatitis B and natural immunity to S. pneumonise.

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Document Details

Document Type
Technical Report
Publication Date
Sep 30, 1995
Accession Number
ADA328384

Entities

People

  • Renata J. Engler

Organizations

  • Walter Reed Army Medical Center

Tags

DTIC Thesaurus Topics

  • Abstracts
  • Active Duty
  • Age Groups
  • Animals
  • Biomedical Research
  • Chemical Compounds
  • Federal Law
  • Health
  • Hepatitis
  • Immunity
  • Immunization
  • Laboratory Animals
  • Macromolecules
  • Materials
  • Molecules
  • Recombinant Dna
  • Standards

Fields of Study

  • Medicine

Readers

  • Immunology
  • Infectious Disease/Epidemiology
  • Naval Personnel Management

Technology Areas

  • Biotechnology