Corneal Damage from Infrared Radiation.

Abstract

This report summarizes our research during the past year on the interaction of 80 ns pulses of infrared radiation produced by a CO2-TEA laser with the cornea. Epithelial damage thresholds were determined for sequences of 1, 2, 8, 32, 128, and 1024 pulses at 10 Hz and for sequences of 1, 2, 8, 32, 128, and 1024 pulses at 16 Hz. Threshold damage is correlated by a power law of the form EDth = CN-alpha in which EDth is the threshold energy density and N is the number of pulses in the sequence. Temperature calculations reveal that the maximum temperature increase on the beam axis 10 micron beneath the anterior tear surface resulting from the different threshold exposures is essentially constant. This result is consistent with a critical peak temperature damage model and suggests that, at least for the multiple-pulse exposures, the damage mechanism may be predominately thermal. Damage threshold measurements on corneas maintained at 21 C indicated that the damage mechanism is indeed predominately thermal.

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Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1997
Accession Number
ADA334135

Entities

People

  • Russel L. Mccally

Organizations

  • Johns Hopkins University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Abstracts
  • Biomedical Research
  • Databases
  • Electromagnetic Radiation
  • Heat Transfer
  • Infrared Radiation
  • Ionizing Radiation
  • Laboratory Animals
  • Laser Beams
  • Lasers
  • Materials
  • Measurement
  • Medical Personnel
  • Radiation
  • Sequences
  • Tea Lasers
  • Temperature Gradients

Fields of Study

  • Physics

Readers

  • Neurotrauma and Rehabilitation Medicine.
  • Pulsed Power and Plasma Physics.
  • Structural Health Monitoring of Composite Structures.

Technology Areas

  • Directed Energy
  • Directed Energy - Pulsed-Laser Deposition